Citric Acid → 2-Methyl-benzaldoxime
反応式
[CH3:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.[Cl-].[OH:11][NH3+:12].[OH-].[Na+].C(O)(=O)CC(CC(O)=O)(C(O)=O)O>O.C(O)C>[CH3:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[N:12][OH:11]参加物
7
実験手順
A mixture of 2-methylbenzaldehyde (10.8 g, 90 mmol), hydroxylammonium chloride (9.4 g, 135 mmol), sodium hydroxide (18.0,0.45 mol), ethanol (80 ml) and water (20 ml) was heated at reflux for 1 h. A solution of citric acid (20 g) in water (700 ml) was added and the mixture was left for crystallisation. The precipitate was collected and recrystallised from water to give 8.6 g of 2-methylbenzaldehyde oxime. M.p. 49.0-49.4° C.
後処理
- temperaturewas heated
- temperatureat reflux for 1 h
- waitthe mixture was left for crystallisation
- customThe precipitate was collected
- customrecrystallised from water
出典と根拠
- ORDレコード
- ord-4069212b558c4bb4a2e7772af3b8b12c
- 出典データセット
- uspto-grants-1997_03
- 特許番号
- US05608069
反応ノート
読み込み中…