反応式
[N:1]1([CH2:6][C:7]2[CH:8]=[C:9]([C:12]3[CH2:13][CH2:14][C:15](=[O:18])[NH:16][N:17]=3)[S:10][CH:11]=2)[CH:5]=[CH:4][N:3]=[CH:2]1.[Na].[N+](C1C=C(S(O)(=O)=O)C=CC=1)([O-])=O.[OH-].[Na+]>O.C(O)(=O)C>[N:1]1([CH2:6][C:7]2[CH:8]=[C:9]([C:12]3[CH:13]=[CH:14][C:15](=[O:18])[NH:16][N:17]=3)[S:10][CH:11]=2)[CH:5]=[CH:4][N:3]=[CH:2]1参加物
7
実験手順
Analoguous to Example 4, the reaction is carried out with 3 g of 4.5-dihydro-6-[4-(imidazol-1-yl-methyl)-thien-2-yl]-3(2H)-pyridazinone (prepared analoguous to Example 3, m.p. 178° to 179° C.), 2.9 g of the sodium salt of 3-nitrobenzenesulfonic acid and 2 g of sodium hydroxide in 40 ml of water. The reaction mixture is neutralized by the addition of 2.5 ml of acetic acid.
出典と根拠
- ORDレコード
- ord-c3b3db63f4814e29a542ad232f754e4d
- 出典データセット
- uspto-grants-1987_05
- 特許番号
- US04667033
関連ノート
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