X-Gal (HCID 65181)｜Huagongshe

이름 및 식별자

우선 이름: X-Gal
IUPAC: (2S,3R,4S,5R,6R)-2-[(5-bromo-4-chloro-1H-indol-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
영어명: 5-Bromo-4-chloro-3-indolyl-beta-D-galactoside
분자식: C14H15BrClNO6
분자량: 408.63

이름 및 동의어

X-Gal7240-90-65-Bromo-4-chloro-3-indolyl beta-galactosideV595OG374W5-bromo-4-chloro-1H-indol-3-yl beta-D-galactopyranoside5-bromo-4-chloroindol-3-yl beta-D-galactopyranosidebeta-D-Galactopyranoside, 5-bromo-4-chloro-1H-indol-3-ylRefChem:1021685-bromo-4-chloro-3-indolyl-beta D-galactopyranoside230-640-85-Bromo-4-chloro-3-(beta-D-galactopyranosyloxy)indoleBCIG

이름 더 보기

X-β-GAL5-BROMO-4-CHLORO-3-INDOLYL-β-D-GALACTOPYRANOSIDE (X-GAL)Bromo Dβ-D-GaLabs9126X-BETA-GALX-gal/BCIGoro-3-indoL

5-Bromo-4-chloro-3-indolyl-beta-D-galactosideMFCD000056665-Bromo-4-chloro-3-indolyl beta-D-galactopyranosideC14H15BrClNO6(2S,3R,4S,5R,6R)-2-[(5-bromo-4-chloro-1H-indol-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol5-Bromo-4-chloroindol-3-yl-beta-D-galactopyranoside.beta.-D-Galactopyranoside, 5-bromo-4-chloro-1H-indol-3-ylM02699

데이터베이스 식별자

CAS: 7240-90-6
PubChem CID: 65181
DTXSID: DTXSID901349452
ChEMBL: CHEMBL1242856
ChEBI: CHEBI:75055
UNII: V595OG374W
EC Number: 230-640-8
Nikkaji: J212.257J

물성

구조 계산 물성

XLogP: 1.2
극성 표면적: 115 Å²
수소 결합 공여자 수: 5
수소 결합 수용자 수: 6
회전 가능 결합 수: 3
무거운 원자 수: 23
형식 전하: 0
복잡도: 421

실험 및 물리화학적 성질

Physical DescriptionSolid; [Merck Index] White powder; [Sigma-Aldrich MSDS]

물리화학적 성질

녹는점: 230 °C · 230 °C
끓는 점: 673.9 · 673.9±55.0 °C(Predicted)
밀도: 1.5563 · 1.5563 (rough estimate)
굴절률: 1.611 · 1.6110 (estimate)
저장 조건: -20 °C · -20°C
용해도: 100 mM에 · DMSO에서 100 mM에 용해됩니다.
물리적 상태: 가루
산도 계수 (pKa): 12.74 · 12.74±0.70(Predicted)
색상: 하얀색
냄새: 냄새 없는
Merck: 14 · 14,10074
BRN: 1402009 · 1402009
안정성: 안정적인. 강한 산화제와 호환되지 않습니다.
InChI: 1S/C14H15BrClNO6/c15-5-1-2-6-9(10(5)16)7(3-17-6)22-14-13(21)12(20)11(19)8(4-18)23-14/h1-3,8,11-14,17-21H,4H2/t8-,11+,12+,13-,14-/m1/s1
InChIKey: OPIFSICVWOWJMJ-AEOCFKNESA-N
SMILES: OC[C@H]1O[C@@H](Oc2c[nH]c3ccc(Br)c(Cl)c23)[C@H](O)[C@@H](O)[C@H]1O

화학적 성질

White Powder

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 20% (2 of 10) of reports.

Warning

H302 (80%): Harmful if swallowed [Warning Acute toxicity, oral]；H312 (80%): Harmful in contact with skin [Warning Acute toxicity, dermal]；H332 (80%): Harmful if inhaled [Warning Acute toxicity, inhalation]

P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 10 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 2 of 10 reports by companies.；There are 2 notifications provided by 8 of 10 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information5-Bromo-4-chloro-3-indolyl-beta-D-galactoside: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryMay cause irritation; [Sigma-Aldrich MSDS] See Indole and 5-Bromo-4-chloro-3-indoxyl phosphate.

Hazard Classes and CategoriesAcute Tox. 4 (80%)；Acute Tox. 4 (80%)；Acute Tox. 4 (80%)

규제 정보

Regulatory Information5-Bromo-4-chloro-3-indolyl-beta-D-galactoside: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk: 3
HS 번호: 29389090
risk_code: 36/37/38
hazard_code: Xi
safety_code: 24/25-37/39-26
위험 등급: IRRITANT
F 고인화성물질: 8-10-21
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 1건

Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; used in biochemical assays and in diagnosis as indicators, especially in the form of enzyme substrates. Synonym: chromogens (not to be confused with pigment-synthesizing bacteria also called chromogens).

용도 및 제조

UsesChromogenic substrate of beta-galactosidase used in histological staining and cloning experiments of bacteria; [Merck Index]

응용 분야

용도A substrate for -Galactosidase that is converted by the enzyme into an intense indigo-blue chromophore (615 nm)

공급사50 곳

北京华美互利生物化工010-56205725 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

INTATRADE GmbH+49 3493/605464 · [email protected]

南京百芙利科技有限责任公司25-25-58740604 15951658055 · [email protected]

추가 설명 · 1건

정의ChEBI: An indolyl carbohydrate that is the beta-D-galactoside of 3-hydroxy-1H-indole in which the indole moiety is substituted at positions 4 and 5 by chlorine and bromine, respectively. It is used to test for he presence of an enzyme, beta-galactosidase, which cleaved the glycosidic bond to give 5-bromo-4-chloro-3-hydroxy-1H-indole, which immediately dimerises to give an intensely blue product.