Propylene Glycol → Florfenicol Flunixin

HRID 1006517

반응식

HRID 1006517 반응식
C(O)C(O)C.[CH3:6][S:7]([C:10]1[CH:11]=[CH:12][C:13]([C@@H:16]([OH:26])[C@H:17]([NH:20][C:21]([CH:23]([Cl:25])[Cl:24])=[O:22])[CH2:18][F:19])=[CH:14][CH:15]=1)(=[O:9])=[O:8].[CH3:27][C:28]1[C:33]([NH:34][C:35]2[N:40]=[CH:39][CH:38]=[CH:37][C:36]=2[C:41]([OH:43])=[O:42])=[CH:32][CH:31]=[CH:30][C:29]=1[C:44]([F:47])([F:46])[F:45].CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>CN1CCCC1=O>[CH3:6][S:7]([C:10]1[CH:11]=[CH:12][C:13]([C@@H:16]([OH:26])[C@H:17]([NH:20][C:21]([CH:23]([Cl:25])[Cl:24])=[O:22])[CH2:18][F:19])=[CH:14][CH:15]=1)(=[O:9])=[O:8].[CH3:27][C:28]1[C:33]([NH:34][C:35]2[N:40]=[CH:39][CH:38]=[CH:37][C:36]=2[C:41]([OH:43])=[O:42])=[CH:32][CH:31]=[CH:30][C:29]=1[C:44]([F:46])([F:45])[F:47]

참가 물질

5

반응물 3

HCID 1030Propylene GlycolHCID 39212Flunixin MeglumineHCID 114811Florfenicol

생성물 1

HCID 86602307Florfenicol Flunixin

시약·촉매·용매 1

HCID 13387N-methyl-2-pyrrolidone용매

실험 절차

The N-methyl-2-pyrrolidone, propylene glycol and approximately 90% of the PEG 300 required were charged to the compounding vessel and mixed well. The florfenicol and flunixin meglumine were added with mixing until all solids were dissolved. The volume was adjusted with the remaining PEG 300.

후처리

  1. additionmixed well
  2. additionwith mixing until all solids
  3. dissolutionwere dissolved

출처 및 근거

ORD 기록
ord-367a363c259c4279b1582a1a91f894dd
출처 데이터셋
uspto-grants-2004_09
특허 번호
US06790867B2

연결된 노트

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