Propylene Glycol → Florfenicol Flunixin
반응식
C(O)C(O)C.[CH3:6][S:7]([C:10]1[CH:11]=[CH:12][C:13]([C@@H:16]([OH:26])[C@H:17]([NH:20][C:21]([CH:23]([Cl:25])[Cl:24])=[O:22])[CH2:18][F:19])=[CH:14][CH:15]=1)(=[O:9])=[O:8].[CH3:27][C:28]1[C:33]([NH:34][C:35]2[N:40]=[CH:39][CH:38]=[CH:37][C:36]=2[C:41]([OH:43])=[O:42])=[CH:32][CH:31]=[CH:30][C:29]=1[C:44]([F:47])([F:46])[F:45].CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>CN1CCCC1=O>[CH3:6][S:7]([C:10]1[CH:11]=[CH:12][C:13]([C@@H:16]([OH:26])[C@H:17]([NH:20][C:21]([CH:23]([Cl:25])[Cl:24])=[O:22])[CH2:18][F:19])=[CH:14][CH:15]=1)(=[O:9])=[O:8].[CH3:27][C:28]1[C:33]([NH:34][C:35]2[N:40]=[CH:39][CH:38]=[CH:37][C:36]=2[C:41]([OH:43])=[O:42])=[CH:32][CH:31]=[CH:30][C:29]=1[C:44]([F:46])([F:45])[F:47]참가 물질
5
실험 절차
The N-methyl-2-pyrrolidone, propylene glycol and approximately 90% of the PEG 300 required were charged to the compounding vessel and mixed well. The florfenicol and flunixin meglumine were added with mixing until all solids were dissolved. The volume was adjusted with the remaining PEG 300.