4'-Methoxyacetophenone → 1-(4-Methoxy-phenyl)-5-phenyl-penta-2,4-diene-1-one

HRID 10122

반응식

HRID 10122 반응식
[CH:1](=O)/[CH:2]=[CH:3]/[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH3:11][C:12]([C:14]1[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=1)=[O:13].[OH-].[Na+]>C(O)C>[CH3:21][O:20][C:17]1[CH:18]=[CH:19][C:14]([C:12](=[O:13])[CH:11]=[CH:1][CH:2]=[CH:3][C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)=[CH:15][CH:16]=1

참가 물질

5

반응물 3

HCID 74764'-MethoxyacetophenoneHCID 14798Sodium HydroxideHCID 637511Cinnamaldehyde

생성물 1

HCID 33966601-(4-Methoxy-phenyl)-5-phenyl-penta-2,4-diene-1-one수율 72%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

2 ml of trans-cinnamaldehyde and 2.5 g of 4-methoxy acetophenone were dissolved in 50 ml of ethanol at room temperature. 10 ml of sodium hydroxide solution was then added and stirred for 12 h to form yellow solid precipitation. Filtering the precipitation to obtain the compound 1, with yield of 72% and purity of 96.3%. FIG. 1 and FIG. 2 respectively show the NMR and UV spectrum of compound 1; wherein the maximum adsorptive wavelength of compound 1 is 345 nm, and the adsorptive coefficient ε is 4.5×104, both listed on Table 1.

후처리

  1. customto form yellow
  2. customsolid precipitation
  3. filtrationFiltering
  4. customthe precipitation

출처 및 근거

ORD 기록
ord-8515cfed68d2474e998cef70299e4581
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07094457B2

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