Sulfuric Acid → Benzidine

HRID 1071897

반응식

HRID 1071897 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1S(O)(=O)=O)([O-])=O.[N+:14]([C:17]1[CH:18]=[C:19](S([O-])(=O)=O)[CH:20]=[CH:21][CH:22]=1)([O-])=O.[Na+].[N+](C1C=CC=CC=1)([O-])=O.[OH-].[Na+].N(C1C=CC=CC=1)NC1C=CC=CC=1.S(=O)(=O)(O)O>[Zn]>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([C:20]2[CH:19]=[CH:18][C:17]([NH2:14])=[CH:22][CH:21]=2)=[CH:6][CH:5]=1

참가 물질

8

반응물 6

HCID 1118Sulfuric AcidHCID 66642-Nitrobenzenesulphonic acidHCID 7416NitrobenzeneHCID 14798Sodium HydroxideHCID 31222HydrazobenzeneHCID 31389Sodium 3-nitrobenzenesulfonate

생성물 1

HCID 7111Benzidine

시약·촉매·용매 1

HCID 23994Zinc촉매

실험 절차

A 2-nitrobenzenesulfonic acid derivative (e.g. sodium 2-nitrobenzenesulfonate) or a 3-nitrobenzenesuflonic acid derivative (e.g. sodium 3-nitrobenzenesulfonate) and nitrobenzene are treated with zinc dust in the presence of an alkali (e.g. sodium hydroxide) and the resulting hydrazobenzene derivative is treated with sulfuric acid, to give the corresponding 4,4′-diaminobiphenyl derivative. This is diazotized using sodium nitrite under acidic conditions in the presence of hydrochloric acid, followed by reaction with sodium azide, to give the desired product.

출처 및 근거

ORD 기록
ord-c9827427759e481e95f5eb7980b46efa
출처 데이터셋
uspto-grants-2005_06
특허 번호
US06908719B1

연결된 노트

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