Sulfuric Acid → Benzidine

HRID 1071900

반응식

HRID 1071900 반응식
[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1C(O)=O)([O-])=O.[N+](C1C=C(C=CC=1)C(O)=O)([O-])=O.[N+:25]([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)([O-])=O.[OH-].[Na+].N(C1C=CC=CC=1)NC1C=CC=CC=1.S(=O)(=O)(O)O>[Zn]>[NH2:25][C:28]1[CH:33]=[CH:32][C:31]([C:10]2[CH:11]=[CH:12][C:4]([NH2:1])=[CH:5][CH:9]=2)=[CH:30][CH:29]=1

참가 물질

8

반응물 6

HCID 1118Sulfuric AcidHCID 7416NitrobenzeneHCID 84973-Nitrobenzoic acidHCID 110872-Nitrobenzoic acidHCID 14798Sodium HydroxideHCID 31222Hydrazobenzene

생성물 1

HCID 7111Benzidine

시약·촉매·용매 1

HCID 23994Zinc촉매

실험 절차

A 2-nitrobenzoic acid derivative (e.g. sodium 2-nitrobenzoate) or a 3-nitrobenzoic acid derivative (e.g. sodium 3-nitrobenzoate) and nitrobenzene are treated with zinc dust in the presence of an alkali (e.g. sodium hydroxide) and the resulting hydrazobenzene derivative is treated with sulfuric acid, to give the corresponding 4,4′-diaminobiphenyl derivative. This is diazotized using sodium nitrite under acidic conditions in the presence of hydrochloric acid, followed by reaction with sodium azide, to give the desired product.

출처 및 근거

ORD 기록
ord-584fb01b4f5e42328545d2572c0559c7
출처 데이터셋
uspto-grants-2005_06
특허 번호
US06908719B1

연결된 노트

불러오는 중…