Hydrochloric Acid → 4-Chloro-2-cyclopropyl-6-(3-fluoro-azetidin-1-yl)-pyrimidine

HRID 1238224노트

반응식

[C:18](=[O:19])([O-:20])[O-:21].[CH3:24][O:25][CH2:26][CH:27]([OH:28])[CH3:29].[Cl:1][c:2]1[n:3][c:4]([CH:9]2[CH2:10][CH2:11]2)[n:5][c:6]([Cl:8])[cH:7]1.[ClH:12].[F:13][CH:14]1[CH2:15][NH:16][CH2:17]1.[K+:22].[K+:23]>>[c:2]1([N:16]2[CH2:15][CH:14]([F:13])[CH2:17]2)[n:3][c:4]([CH:9]2[CH2:10][CH2:11]2)[n:5][c:6]([Cl:8])[cH:7]1