Alpha-Aminobutyric Acid → 2-(Acetylamino)butanoic acid

HRID 1241487

반응식

HRID 1241487 반응식
[NH2:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4].[C:8](OC(=O)C)(=[O:10])[CH3:9]>C(O)(=O)C>[C:8]([NH:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4])(=[O:10])[CH3:9]

참가 물질

4

반응물 2

HCID 6657Alpha-Aminobutyric AcidHCID 7918Acetic Anhydride

생성물 1

HCID 3061072-(Acetylamino)butanoic acid

시약·촉매·용매 1

HCID 176Acetic Acid용매

반응 조건

온도
100 °C

실험 절차

163 g (1.58 mol) 2-aminobutanoic acid are dissolved in acetic acid, and 242 g (2.37 mol) acetic anhydride are added dropwise. The mixture is stirred for 2 h at 100° C. until completion of reaction, then the solution evaporated to dryness in vacuo. The solid residue is suspended in ethyl acetate, filtered and washed with diethyl ether.

후처리

  1. customthe solution evaporated to dryness in vacuo
  2. filtrationfiltered
  3. washwashed with diethyl ether

출처 및 근거

ORD 기록
ord-1f439a35aca34f5790b48824d706b12d
출처 데이터셋
uspto-grants-2006_10
특허 번호
US07115602B2

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