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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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Hydrochloric Acid → 2,4-Imidazolidinedione, 5-(4-methoxy-3-methylphenyl)-5-(4-methoxyphenyl)-

HRID 1278255
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HRID 1278255 반응식
[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([C:7]([C:9]2[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][CH:10]=2)=O)=[CH:5][C:4]=1[CH3:19].[C-]#[N:21].[K+].[C:23](=[O:26])([O-])O.[NH4+].[CH:28]([NH2:30])=[O:29].Cl>O>[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([C:7]2([C:9]3[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][CH:10]=3)[NH:21][C:28](=[O:29])[NH:30][C:23]2=[O:26])=[CH:5][C:4]=1[CH3:19]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

7

반응물 5

HCID 313Hydrochloric AcidHCID 713FormamideHCID 9032Potassium CyanideHCID 14013Ammonium BicarbonateHCID 19864229HCID 19864229, 화합물

생성물 1

HCID 30581982,4-Imidazolidinedione, 5-(4-methoxy-3-methylphenyl)-5-(4-methoxyphenyl)-

시약·촉매·용매 1

HCID 962
Water
용매
2회

실험 절차

34.5 Grams of 4,4'-dimethoxy-3-methylbenzophenone, 66.7 g of potassium cyanide and 232.2 g of ammonium hydrogencarbonate were heated to 120° C. together with 500 ml. of formamide and 100 ml. of water with stirring in an autoclave. After 72 hours, the reaction liquid was made acidic with concentrated hydrochloric acid, mixed with water and allowed to stand overnight. The precipitates thus formed were filtered out. The precipitates were dissolved in acetone, decolorized by active carbon under heating and recrystallized from hexane-acetone to obtain 22.7 g of 5-(4-methoxy-3-methylphenyl)-5-(4-methoxyphenyl)-hydantoin in the form of white crystals.

후처리

  1. customthe reaction liquid
  2. waitto stand overnight
  3. customThe precipitates thus
  4. customformed
  5. filtrationwere filtered out
  6. dissolutionThe precipitates were dissolved in acetone
  7. temperatureunder heating
  8. customrecrystallized from hexane-acetone

출처 및 근거

ORD 기록
ord-676d664ae2ee41bc83bcef77a20d934f
출처 데이터셋
uspto-grants-1981_07
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US04281009

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