Methyl iodide → 4-Methylheptane-3,5-dione
반응식
[H-].[Na+].O1CCC[CH2:4]1.[CH3:8][CH2:9][C:10](=[O:16])[CH2:11][C:12](=[O:15])[CH2:13][CH3:14].IC>O>[CH3:4][CH:11]([C:10](=[O:16])[CH2:9][CH3:8])[C:12](=[O:15])[CH2:13][CH3:14]참가 물질
6
실험 절차
To 0.02 mol sodium hydride was added 100 ml anhydrous tetrahydrofuran, slowly added dropwise 0.02 mol 3,5-heptandione at room temperature. Upon completion, the mixture was stirred for 0.5 hours, then 0.04 mol iodomethane was slowly added dropwise. After stirred at room temperature for 10 hours, 20 ml water was added. White solid was precipitated. The solid was filtered, washed with water, and dried to give 4-methyl-3,5-heptandione as a white solid, and the yield was 94%. m.p. was 91-92° C.
후처리
- stirringAfter stirred at room temperature for 10 hours
- customWhite solid was precipitated
- filtrationThe solid was filtered
- washwashed with water
- customdried
출처 및 근거
- ORD 기록
- ord-215ad9bed3a34087a85ae1671f74959f
- 출처 데이터셋
- uspto-grants-2008_06
- 특허 번호
- US07388061B2
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