Hydroxycitronellal → Citronellol

HRID 1438774

반응식

HRID 1438774 반응식
O[CH2:2]/[C:3](=[CH:5]\[CH2:6][CH2:7][CH:8]([CH2:10][CH2:11][OH:12])[CH3:9])/[CH3:4].CC(CC=O)CCCC(O)(C)C.CC(=CCC/C(=C/CO)/C)C.OC/C=C(/C)\CCC=C(C)C.CC1(C)C2CC1CCC2=C.CC(C)=CCCC(C=C)=C.Cl>>[CH3:2][C:3](=[CH:5][CH2:6][CH2:7][CH:8]([CH2:10][CH2:11][OH:12])[CH3:9])[CH3:4]

참가 물질

7

반응물 6

HCID 7888HydroxycitronellalHCID 14896Beta-PineneHCID 637566GeraniolHCID 643820NerolHCID 19805005Myrcene hydrochlorideHCID 77134639(Z)-2,6-dimethyloct-2-ene-1,8-diol

생성물 1

HCID 8842Citronellol

실험 절차

A primary use for hydroxycitronellol is as an intermediate in the synthesis of hydroxycitronellal, (7-hydroxy-3,7-dimethyloctan-1-al), a widely used perfumery material. Conventionally, in this synthesis, a mixture of geraniol and nerol is prepared from beta-pinene via myrcene hydrochloride and is partially hydrogenated to produce citronellol. Citronellol is then hydrated under acid conditions to produce hydroxycitronellol. It has also been made from myrcene by preparing the dihydrochloride and then chlorodihydrogeranyl acetate, followed by saponification and hydrogenation.1

후처리

  1. customConventionally, in this synthesis

출처 및 근거

ORD 기록
ord-d9fcde7c0b9e46e8aed934fd9f036ca6
출처 데이터셋
uspto-grants-1977_11
특허 번호
US04056573

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