Prepare using the method of Example 103 with palladium (II) acetate (0.011 g, 0.05 mmol), anhydrous acetonitrile (8 mL), triphenylphosphine (0.051 g, 0.19 mmol), distilled water (2 mL), 2-methoxy-5-pyrimidineboronic acid (0.75 g, 4.87 mmol), 2-(4-bromophenyl)-4-{2-[(2R)-2-methylpyrrolidin-1-yl]ethyl}-5-methyl-1,3-oxazole (See Intermediate 73) (0.85 g, 2.43 mmol) and potassium carbonate (0.1.01 g, 7.30 mmol). Additionally recrystallise from acetonitrile/ethyl acetate to give the title compound as a cream coloured solid (0.016 g): MS (m/e): 379(M+1).
