반응식
[C@@H]1([N:9]2[CH:17]=[C:15]([CH3:16])[C:13](=[O:14])NC2=O)O[C@H](CO)[C@@H](O)C1.C1N(CCO)CCN(CCS(O)(=O)=O)C1.C1N=C(N)C2N=CN([C@@H]3O[C@H](COP(OP(OC[C@H]4O[C@@H](N5C=C(C(N)=O)CC=C5)[C@H](O)[C@@H]4O)(O)=O)(O)=O)[C@@H](O)[C@H]3O)C=2N=1.C1C=[N+]([C@@H]2O[C@H](COP(OP(OC[C@H]3O[C@@H](N4C5N=CN=C(N)C=5N=C4)[C@H](OP(O)(O)=O)[C@@H]3O)(O)=O)(O)=O)[C@@H](O)[C@H]2O)C=C(C(N)=O)C=1.C(C=C)=O.CCN(C(SSC(N(CC)CC)=S)=S)CC.C(=O)CC.[CH:149](=O)[C:150]1[CH:155]=[CH:154][CH:153]=[CH:152][CH:151]=1>>[CH2:155]([C:150]1[CH:149]=[CH:16][C:15]([CH:13]=[O:14])=[C:17]([NH2:9])[C:151]=1[CH2:152][CH3:153])[CH3:154]참가 물질
9
실험 절차
Materials: SDA was prepared by acid hydrolysis of the corresponding bioacetal supplied by the Department of Pharmaceutical Development at our Institute. [3H]-Thymidine was purchased from New England Nuclear, Boston, Mass. Concanavalin A, horse serum, RPMI-1640 and HEPES were from Gibco, Grand Island, N.Y. NAD and NADP were purchased from Boehringer, Mannheim. Acrolein and disulfiram were obtained from Aldrich Chemical Co., Milwaukee, Wis. Propionaldehyde and benzaldehyde were from Eastman Kodak Chemical Co., Rochester, N.Y. Diethyl aminobenzaldehyde (DEAB) was kindly provided by Dr. John Hilton, Johns Hopkins School of Medicine, Baltimore, Md.
후처리
- customMaterials: SDA was prepared by acid hydrolysis of the corresponding bioacetal
출처 및 근거
- ORD 기록
- ord-5424f1799aac4456a064308777a3601d
- 출처 데이터셋
- uspto-grants-1994_12
- 특허 번호
- US05374658
연결된 노트
불러오는 중…