Hydrochloric Acid → HCID 21500551, 화합물

HRID 1658413노트

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HRID 1658413 반응식
[CH3:1][C:2]1[CH:15]=[C:14]2[C:5]([O:6][C:7]3[CH:8]=[CH:9][C:10]([C:16]([O:18][CH3:19])=[O:17])=[CH:11][C:12]=3[CH2:13]2)=[CH:4][CH:3]=1.ClC(Cl)C.[C:24](Cl)(=[O:26])[CH3:25].[Cl-].[Cl-].[Cl-].[Al+3].Cl>O>[C:24]([C:4]1[CH:3]=[C:2]([CH3:1])[CH:15]=[C:14]2[C:5]=1[O:6][C:7]1[CH:8]=[CH:9][C:10]([C:16]([O:18][CH3:19])=[O:17])=[CH:11][C:12]=1[CH2:13]2)(=[O:26])[CH3:25]

참가 물질

7

반응물 5

HCID 313Hydrochloric AcidHCID 63651,1-DichloroethaneHCID 6367Acetyl chlorideHCID 6451240Aluminum(III) ChlorideHCID 21500836Methyl 7-methyl-9H-xanthene-2-carboxylate

생성물 1

HCID 21500551HCID 21500551, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of 130 g. of methyl 7-methylxanthene-2-carboxylate in 200 ml. of dichloroethane is cooled to -5°C and to the cooled solution are added 4.95 ml. of acetyl chloride and then 17.0 g. of aluminum trichloride. The resultant solution is stirred at room temperature for 1.75 hours. After this time, the solution is poured into a mixture of 300 g. of ice, 700 ml. of water and 20 ml. of concentrated hydrochloric acid. The mixture is then extracted with three 500 ml. portions of methylene chloride. The combined extracts are washed with 10% aqueous potassium hydroxide solution and the washed solution evaporated to give methyl 5-acetyl-7-methylxanthene-2-carboxylate.

후처리

  1. additionA mixture of 130 g
  2. additionare added 4.95 ml
  3. additionAfter this time, the solution is poured into a mixture of 300 g
  4. extractionThe mixture is then extracted with three 500 ml
  5. washThe combined extracts are washed with 10% aqueous potassium hydroxide solution
  6. customthe washed solution evaporated

출처 및 근거

ORD 기록
ord-1e6adc91621a48d4aa52a22f253dd61f
출처 데이터셋
uspto-grants-1976_06
특허 번호
US03963752

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