Ethylenediamine → N-Cyclohexyl-1,2-ethanediamine

HRID 1742179

반응식

HRID 1742179 반응식
[C:1]1(=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:8]([NH2:11])[CH2:9][NH2:10]>C(O)C.O=[Pt]=O>[CH:1]1([NH:10][CH2:9][CH2:8][NH2:11])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

5

반응물 2

HCID 3301EthylenediamineHCID 7967Cyclohexanone

생성물 1

HCID 21922N-Cyclohexyl-1,2-ethanediamine

시약·촉매·용매 2

HCID 345198Adams' catalyst촉매HCID 702Ethanol용매2회

실험 절차

Cyclohexanone (50 g) and ethylene diamine (60 g) were mixed in ethanol (50 ml) at room temperature and allowed to stand for one hour. Meanwhile Adams catalyst (1 g) in ethanol (20 ml) was pre-reduced on a Parr apparatus at 60 p.s.i. under hydrogen for one hour. The imine solution was added to the hydrogenation flask and reduced at 60 p.s.i. for 18 hours. The catalyst was removed by filtration and the ethanol removed under vacuum. N-Cyclohexyl ethylene diamine was obtained on distillation of the crude product collecting the fraction boiling between 110°-120° C. at 20 ram.

후처리

  1. waitunder hydrogen for one hour
  2. waitfor 18 hours
  3. customThe catalyst was removed by filtration
  4. customthe ethanol removed under vacuum

출처 및 근거

ORD 기록
ord-08c1431152a74eacbc3095d247238e08
출처 데이터셋
uspto-grants-1994_08
특허 번호
US05338735

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