Hydrochloric Acid → HCID 14576890, 화합물

HRID 1904619노트

반응식

HRID 1904619 반응식
[CH3:1][O:2][C:3]1[CH:16]=[CH:15][C:6]([C:7]([CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])=[O:8])=[CH:5][CH:4]=1.[OH-].[Na+].[BH4-].[Na+].Cl>O>[OH:8][CH:7]([C:6]1[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:16][CH:15]=1)[CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13]

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 2668175-(4-Methoxyphenyl)-5-oxopentanoic acidHCID 4311764Sodium borohydride

생성물 1

HCID 14576890HCID 14576890, 화합물수율 98.2%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To 4.44 g of 4-(4-methoxybenzoyl)butanoic acid was added a solution of 0.8 g of sodium hydroxide in 30 ml of water, and to this solution was added 1.5 g of sodium borohydride, followed by stirring of the mixture at room temperature for 24 hours. The mixture was neutralized with diluted hydrochloric acid, extracted with ether, washed with water and dried, followed by evaporation of the solvent to give 4.4 g of 5-hydroxy-5-(4-methoxyphenyl)pentanoic acid as yellow oily product.

후처리

  1. extractionextracted with ether
  2. washwashed with water
  3. customdried
  4. customfollowed by evaporation of the solvent

출처 및 근거

ORD 기록
ord-83207683d7da42e3a75ebbd57cdb8930
출처 데이터셋
uspto-grants-1989_06
특허 번호
US04839360

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