Hydrochloric Acid → HCID 178463602, 화합물

HRID 1905845노트

반응식

HRID 1905845 반응식
[NH2:1][C:2]([NH2:4])=[S:3].[CH2:5]([NH:7][C:8]1N=C(NCC)N=[C:10](Cl)[N:9]=1)[CH3:6].[OH-].[Na+].Cl>O1CCOCC1.O>[CH2:5]([NH:7][C:8]1[N:9]=[CH:10][N:4]=[C:2]([SH:3])[N:1]=1)[CH3:6]

참가 물질

7

반응물 4

HCID 313Hydrochloric AcidHCID 5216SimazineHCID 14798Sodium HydroxideHCID 2723790Thiourea

생성물 1

HCID 178463602HCID 178463602, 화합물

시약·촉매·용매 2

HCID 962Water용매HCID 312751,4-Dioxane용매

실험 절차

A mixture of 1.5 g of thiourea and 4 g of 2,4-bis(ethylamino)-6-chloro-1,3,5-triazine in a mixture of 20 ml of dioxane and 20 ml of water is refluxed with stirring for 2 hours in 100 ml flask. After cooling, the mixture is mixed with 1.6 g of 50% sodium hydroxide and stirred for 10 minutes. The resulting mixture is neutralized with hydrochloric acid and extracted with ethyl acetate. The extract is concentrated under reduced pressure to give 4 g of 2,4-bis(ethylamino-6-mercapto-1,3,5-triazine. The product can be used for preparation of the objective compound without isolation.

후처리

  1. temperatureis refluxed
  2. temperatureAfter cooling
  3. stirringstirred for 10 minutes
  4. extractionextracted with ethyl acetate
  5. concentrationThe extract is concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-ece3f5e15c1949ef980cc2538cacbfc1
출처 데이터셋
uspto-grants-1987_03
특허 번호
US04648898

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