Cyclohexanol → 5-Methyloxepan-2-one

HRID 1976871

반응식

[CH3:1][CH:2]1[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][CH2:3]1.CC1CCC([OH:16])CC1.C1(=O)CCCCC1.C1(O)CCCCC1>>[CH3:1][CH:2]1[CH2:3][CH2:4][O:8][C:5](=[O:16])[CH2:6][CH2:7]1

참가 물질

반응물 4

HCID 7966Cyclohexanol

HCID 7967Cyclohexanone

HCID 115244-Methylcyclohexanol

HCID 115254-Methylcyclohexanone

생성물 1

HCID 111160855-Methyloxepan-2-one수율 45.6%

실험 절차

The procedure of Example 25 was repeated, except that 4-methylcyclohexanone (2 mmol) and 4-methylcyclohexanol (20 mmol) were respectively used in stead of cyclohexanone and cyclohexanol. As a result, γ-methyl-ε-caprolactone was formed in yield of 45.6% (on 4-methylcyclohexanone basis).

출처 및 근거

ORD 기록: ord-e9be06758656493f86556ad392cedec9
출처 데이터셋: uspto-grants-2001_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06229023B1

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