Diboron tetrahydroxide → (1-Methyl-1H-benzimidazol-6-yl)boronic acid

HRID 2018238

반응식

HRID 2018238 반응식
[CH3:1][n:2]1[c:10]([c:5]2[n:4][cH:3]1)[cH:9][c:8](Br)[cH:7][cH:6]2.[OH:11][B:12](B(O)O)[OH:13]>>[CH3:1][n:2]1[c:10]([c:5]2[n:4][cH:3]1)[cH:9][c:8]([B:12]([OH:13])[OH:11])[cH:7][cH:6]2

참가 물질

8

반응물 2

HCID 10986154Diboron tetrahydroxideHCID 235376446-Bromo-1-methyl-1H-benzimidazole

생성물 1

HCID 46738679(1-Methyl-1H-benzimidazol-6-yl)boronic acid

시약·촉매·용매 5

HCID 516892Sodium Bicarbonate시약HCID 83681Tris(1,1-dimethylethyl)phosphine촉매HCID 167845palladium(II) acetate촉매HCID 64052-Methyl-2-butanol용매HCID 117669-Phenylanthracene내부 표준

반응 조건

온도
110 °C

출처 및 근거

ORD 기록
ord-bde3c0b0ce9e412db96d10552c271799
출처 데이터셋
39k HTE dataset from Pfizer
원본 링크
출처 보기

연결된 노트

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