Hydrochloric Acid → HCID 14452901, 화합물

HRID 2165260노트

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HRID 2165260 반응식
[Cl:1][C:2]1[C:7]([N+:8]([O-])=O)=[C:6]([Cl:11])[CH:5]=[C:4]([CH2:12][CH3:13])[N:3]=1.Cl[Sn]Cl.Cl.[OH-].[Na+]>>[NH2:8][C:7]1[C:2]([Cl:1])=[N:3][C:4]([CH2:12][CH3:13])=[CH:5][C:6]=1[Cl:11]

참가 물질

5

반응물 4

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 24479Stannous ChlorideHCID 14452905HCID 14452905, 화합물

생성물 1

HCID 14452901HCID 14452901, 화합물

실험 절차

9 g (40.7 mmol) of 2,4-dichloro-6-ethyl-3-nitropyridine are introduced into a solution of 33 g (0.146 mol) of SnCl2. 2H2O in 100 ml of 36% strength HCl and the mixture is boiled under reflux for 30 minutes. It is then cooled and stirred into 400 ml of 12% strength NaOH with cooling. It is extracted three times using 150 ml of dichloromethane each time and the extract is dried using Na2SO4 and evaporated.

후처리

  1. temperatureunder reflux for 30 minutes
  2. temperatureIt is then cooled
  3. temperaturewith cooling
  4. extractionIt is extracted three times
  5. customthe extract is dried
  6. customevaporated

출처 및 근거

ORD 기록
ord-63f2e89df7d746b9bab1be7990dff5b7
출처 데이터셋
uspto-grants-1990_07
특허 번호
US04939262

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