Hydrochloric Acid → Phenylthioethanethiol

HRID 223653노트

반응식

HRID 223653 반응식
[C:1]1([S:7][CH2:8][CH2:9]O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1([SH:17])C=CC=CC=1.C1OC1.[OH-].[K+].NC(N)=S.Cl.O.NN>C1(C)C=CC=CC=1>[C:1]1([S:7][CH:8]([SH:17])[CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

9

반응물 7

HCID 313Hydrochloric AcidHCID 6354Ethylene OxideHCID 7969ThiophenolHCID 14797Potassium HydroxideHCID 24654Hydrazine hydrate (1:1)HCID 696852-(Phenylthio)ethanolHCID 2723790Thiourea

생성물 1

HCID 23503969Phenylthioethanethiol

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

77 g of 2-phenylthioethanol, (0.5 mol, prepared from thiophenol and ethylene oxide in the presence of some potassium hydroxide) are maintained for 4 hours under reflux with 40 g of thiourea and 50 g of 37% hydrochloric acid. At 40° C., the reaction mixture is stirred with 50 g of 50% hydrazine hydrate solution for 30 minutes. 100 ml of toluene are added, this is maintained for 30 minutes in the steam bath, the toluene phase is separated off and compressed under vacuum.

후처리

  1. temperatureare maintained for 4 hours
  2. temperaturethis is maintained for 30 minutes in the steam bath
  3. customthe toluene phase is separated off

출처 및 근거

ORD 기록
ord-cf8da0c2aaf54b18a49b46c8662c59e6
출처 데이터셋
uspto-grants-1982_10
특허 번호
US04355185

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