Sodium Hydroxide → p-Trifluoromethoxybenzaldehyde oxime

HRID 2276393

반응식

HRID 2276393 반응식
[F:1][C:2]([F:13])([F:12])[O:3][C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1.[OH-:14].[Na+].[NH2:16]O.Cl>>[F:1][C:2]([F:13])([F:12])[O:3][C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[N:16][OH:14])=[CH:6][CH:5]=1

참가 물질

4

반응물 3

HCID 14798Sodium HydroxideHCID 69573p-(Trifluoromethoxy)benzaldehydeHCID 443297Hydroxyamine hydrochloride

생성물 1

HCID 2777199p-Trifluoromethoxybenzaldehyde oxime수율 94%

실험 절차

In a similar manner as described in Preparation Example 1, by using 4-(trifluoromethoxy)benzaldehyde (38.02 g, 200.0 mmol), sodium hydroxide (12.00 g, 300.0 mmol) and hydrochloric acid hydroxylamine (16.68 g, 240 mmol), a white solid required compound (38.68 g, 188 mmol, 94%) was obtained.

후처리

  1. customIn a similar manner as described in Preparation Example 1

출처 및 근거

ORD 기록
ord-2d1b21b657f145ceb454501707d3938c
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09132126B2

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