Dimethyl Sulfoxide → Anisole, m-pentadecyl-

HRID 2276622

반응식

HRID 2276622 반응식
[CH2:1]([C:16]1[CH:17]=[C:18]([OH:22])[CH:19]=[CH:20][CH:21]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15].[CH3:23]S(C)=O.[OH-].[Na+].CI>O>[CH2:1]([C:16]1[CH:17]=[C:18]([O:22][CH3:23])[CH:19]=[CH:20][CH:21]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

참가 물질

6

반응물 4

HCID 679Dimethyl SulfoxideHCID 6328Methyl iodideHCID 14798Sodium HydroxideHCID 68146Hydrogenated cardanol

생성물 1

HCID 578947Anisole, m-pentadecyl-

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To a two necked round bottomed flask with a reflux condenser is added 3-pentadecyl phenol, DMSO, sodium hydroxide followed by dropwise addition of alkylating agent such as methyl iodide with constant stirring at room temperature. The stirring is continued for about 6-8 hrs. The reaction mixture is then poured into deionized water and the organic matter is extracted in diethyl ether, separated the organic layer, washed with water and dried, purified to obtain 3-pentadecyl anisole.

후처리

  1. additionfollowed by dropwise addition
  2. extractionthe organic matter is extracted in diethyl ether
  3. customseparated the organic layer
  4. washwashed with water
  5. customdried
  6. custompurified

출처 및 근거

ORD 기록
ord-0cadd41262b44dd289521f0f2f868abf
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09133089B2

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