Veratraldehyde → [2-(3,4-Dimethoxyphenyl)-6-methylimidazo[1,2-a]pyridin-3-yl]-(6-isocyanohexyl)-amine

HRID 22805

반응식

HRID 22805 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][N:3]=1.[N+:9]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][N+:17]#[C-:18])#[C-:10].[CH3:19][O:20][C:21]1[CH:22]=[C:23]([CH:26]=[CH:27][C:28]=1[O:29][CH3:30])[CH:24]=O>Cl(O)(=O)(=O)=O>[CH3:19][O:20][C:21]1[CH:22]=[C:23]([C:24]2[N:1]=[C:2]3[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][N:3]3[C:10]=2[NH:9][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][N+:17]#[C-:18])[CH:26]=[CH:27][C:28]=1[O:29][CH3:30]

참가 물질

5

반응물 3

HCID 8419VeratraldehydeHCID 153482-Amino-5-methylpyridineHCID 33911051,6-Diisocyanohexane

생성물 1

HCID 22591927[2-(3,4-Dimethoxyphenyl)-6-methylimidazo[1,2-a]pyridin-3-yl]-(6-isocyanohexyl)-amine

시약·촉매·용매 1

HCID 24247Perchloric Acid용매

실험 절차

Compound (20) was prepared according to the general synthesis instructions from 1.0 ml of 2-amino-5-methylpyridine solution (0.1 M, DCM), 0.575 ml of 1,6-diisocyanhexane solution (0.2 M, DCM), 0.500 ml of 3,4-dimethoxybenzaldehyde solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%).

출처 및 근거

ORD 기록
ord-74cd1e47abdc4153b2f6f354406593b6
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06849642B2

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