Undecanenitrile → 2-Decyl-2-oxazoline

HRID 2352193

반응식

HRID 2352193 반응식
[CH2:1]([C:12]#[N:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10]C.C(#N)CCCCCCCCCC.N[CH:27]([OH:29])[CH3:28]>C(O)CCC.O.O.C([O-])(=O)C.[Cd+2].C([O-])(=O)C>[CH2:1]([C:12]1[O:29][CH2:27][CH2:28][N:13]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

참가 물질

6

반응물 3

HCID 16722UndecanenitrileHCID 17092DodecanenitrileHCID 522583Acetaldehyde ammonia

생성물 1

HCID 146517892-Decyl-2-oxazoline수율 64.3%

시약·촉매·용매 2

HCID 6537495Cadmium acetate, dihydrate촉매HCID 2631-Butanol용매

실험 절차

Undecyl cyanide in Example 1 was substituted with 18.13 g (108.4 mmoles) of undecanenitrile and allowed to react with 7.5 ml (121.3) mmoles of aminoethanol in presence of cadmium acetate dihydrate (667 mg; 2.5 mmoles) in 1-butanol under identical reaction conditions. The reaction mixture was worked up following Example 1 and the residue was distilled at 118°-120°/1.2 mm to give 14.72 g (64.3%) of 2-decyl-2oxazoline.

후처리

  1. distillationthe residue was distilled at 118°-120°/1.2 mm

출처 및 근거

ORD 기록
ord-b31973048aac46f39b5157a3a9eac804
출처 데이터셋
uspto-grants-1989_10
특허 번호
US04876249

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