4-Methylmorpholine → (2R)-2-[(N-{[4-((2R,3R)-1-(4-fluorophenyl)-3-{[2-(4-fluorophenyl)-2-hydroxyethyl]thio}-4-oxoazetidin-2-yl)phenoxy]acetyl}glycyl)amino]-4-(4-hydroxyphenyl)butanoic acid

반응식

[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:11](=[O:12])[C@H:10]([S:13][CH2:14][C:15]([C:17]3[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=3)=[O:16])[C@H:9]2[C:24]2[CH:38]=[CH:37][C:27]([O:28][CH2:29][C:30]([NH:32][CH2:33]C(O)=O)=[O:31])=[CH:26][CH:25]=2)=[CH:4][CH:3]=1.CN1CC[O:43][CH2:42]C1.CN(C(ON1N=NC2C=CC=CC1=2)=[N+](C)C)C.[B-](F)(F)(F)F.Br.[NH2:69][C@H:70]([CH2:74][CH2:75][C:76]1[CH:81]=[CH:80][C:79]([OH:82])=[CH:78][CH:77]=1)[C:71]([OH:73])=[O:72].[BH4-].[Na+].C([O-])(=O)C.[NH4+]>CN(C=O)C.CO>[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:11](=[O:12])[C@H:10]([S:13][CH2:14][CH:15]([C:17]3[CH:18]=[CH:19][C:20]([F:23])=[CH:21][CH:22]=3)[OH:16])[C@H:9]2[C:24]2[CH:38]=[CH:37][C:27]([O:28][CH2:29][C:30]([NH:32][CH2:33][C:42]([NH:69][C@H:70]([CH2:74][CH2:75][C:76]3[CH:77]=[CH:78][C:79]([OH:82])=[CH:80][CH:81]=3)[C:71]([OH:73])=[O:72])=[O:43])=[O:31])=[CH:26][CH:25]=2)=[CH:4][CH:3]=1