Hydrochloric Acid → 2-Aminoterephthalic acid
반응식
[NH2:1][C:2]1[CH:11]=[C:10]([C:12]([O:14]C)=[O:13])[CH:9]=[CH:8][C:3]=1[C:4]([O:6]C)=[O:5].Cl>[Br-].C([N+](C)(C)C)CCCCCCCCCCCCCCC.[OH-].[Na+]>[NH2:1][C:2]1[CH:11]=[C:10]([C:12]([OH:14])=[O:13])[CH:9]=[CH:8][C:3]=1[C:4]([OH:6])=[O:5]참가 물질
5
실험 절차
A representative preparation was done as follows: Dimethyl aminoterephthalate (5 g), cetyltrimethyl ammonium bromide catalyst (0.05 g) and aqueous NaOH solution (5%, 300 ml) were taken in a 500 ml round bottom flask, and heated to and held at about 60° C. for about 2 hours. The mixture was then cooled to about 15°-20° C., and acidified with concentrated HCl when the acid of Formula 3 separated as yellow crystals. This was filtered, washed with ice cold water, and dried (yield: 89%).
후처리
- customA representative preparation
- temperatureheated to and
- temperatureThe mixture was then cooled to about 15°-20° C.
- customseparated as yellow crystals
- filtrationThis was filtered
- washwashed with ice cold water
- customdried (yield: 89%)
출처 및 근거
- ORD 기록
- ord-a8157de3536c4b3ab4ef96abe13fc8c2
- 출처 데이터셋
- uspto-grants-1993_11
- 특허 번호
- US05264539
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