Aminoacetaldehyde → 1-(alpha-Phenyl-o-tolyl)imidazole
반응식
[C:1]1([CH2:7][C:8]2[C:9](=[CH:11][CH:12]=[CH:13][CH:14]=2)[NH2:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:15](OC)(OC)OC.[NH2:22][CH2:23][CH:24]=O>C(COC)OC.[Ti](Cl)(Cl)(Cl)Cl>[C:1]1([CH2:7][C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[N:10]2[CH:24]=[CH:23][N:22]=[CH:15]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1참가 물질
6
실험 절차
In the manner given in Preparation 21, α-phenyl-o-toluidine is reacted first with trimethyl orthoformate, the resulting product is reacted with aminoacetaldehyde, dimethyl acetal, and the resulting product of this reaction is heated with titanium tetrachloride in monoglyme to give 1-(α-phenyl-o-tolyl)imidazole.
출처 및 근거
- ORD 기록
- ord-95c6e07595134a3592a956073228a28d
- 출처 데이터셋
- uspto-grants-1976_03
- 특허 번호
- US03941803
반응 노트
불러오는 중…