Ammonia → HCID 18628156, 화합물

HRID 268298

반응식

[CH3:1][C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([N+:10]([O-:12])=[O:11])[CH:5]=1)=[O:3].[BH4-].[Na+].Br.[NH3:16]>>[NH2:16][CH2:1][CH:2]([OH:3])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([N+:10]([O-:12])=[O:11])[CH:5]=1

참가 물질

반응물 4

HCID 222Ammonia

HCID 260Hydrogen Bromide

HCID 8494m-Nitroacetophenone

HCID 4311764Sodium borohydride

생성물 1

HCID 18628156HCID 18628156, 화합물

실험 절차

3-Nitroacetophenone is brominated in the α-position, the bromination product is reduced by means of sodium borohydride to the corresponding bromohydride and this is treated with ammonia. There is obtained rac.-α-(aminomethyl)-3-nitrobenzyl alcohol which melts at 107°-108° (softening from 105°) after crystallization from ethyl acetate-ether.

출처 및 근거

ORD 기록: ord-43b11491cddd49dd992e9585706b5712
출처 데이터셋: uspto-grants-1976_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US03947456

연결된 노트

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