Benzyl Alcohol → Benzoic Acid

HRID 28186

반응식

HRID 28186 반응식
I([O-])(=O)(=O)=[O:2].[Na+].[CH2:7]([OH:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>[OH-].[Na+].[Ru](=O)=O>[C:7]([OH:2])(=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

참가 물질

5

반응물 2

HCID 244Benzyl AlcoholHCID 23667635Sodium periodate

생성물 1

HCID 243Benzoic Acid수율 89%

시약·촉매·용매 2

HCID 82848Ruthenium dioxide촉매HCID 14798Sodium Hydroxide용매

실험 절차

To a stirred suspension of 20 g (94 m mol) sodium periodate in 200 cc of 1 molar sodium hydroxide there was added 0.1 g (0.75 m mol) ruthenium dioxide and 4.32 g (40 m mol) benzyl alcohol. After two hours the reaction was stopped. The mixture was then filtered and the filtrate washed with ether obtaining a neutral fraction comprising benzaldehyde and unreacted benzyl alcohol. The aqueous alkali phase was acidified with sulfuric acid and extracted with ether. There was obtained 4.32 grams of benzoic acid (89% yield).

후처리

  1. filtrationThe mixture was then filtered
  2. washthe filtrate washed with ether obtaining a neutral fraction comprising benzaldehyde and unreacted benzyl alcohol
  3. extractionextracted with ether

출처 및 근거

ORD 기록
ord-6ede1a92eed94cd3931b64ec1fd29d22
출처 데이터셋
uspto-grants-1980_09
특허 번호
US04225694

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