Hydrochloric Acid → 4'-Hexyl[1,1'-biphenyl]-4-carboxylic acid

HRID 328305노트

반응식

HRID 328305 반응식
[CH2:1]([C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17]C(C#N)=[CH:15][CH:14]=2)=[CH:9][CH:8]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].C(O)CO[CH2:24][CH2:25][OH:26].[OH-:28].[Na+].Cl>O>[CH2:1]([C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][C:24]([C:25]([OH:26])=[O:28])=[CH:15][CH:14]=2)=[CH:9][CH:8]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 8117Diethylene GlycolHCID 14798Sodium HydroxideHCID 38764(1,1'-Biphenyl)-4-carbonitrile, 4'-hexyl-

생성물 1

HCID 135545884'-Hexyl[1,1'-biphenyl]-4-carboxylic acid

시약·촉매·용매 1

HCID 962Water용매

실험 절차

5 Gram of 4-n-hexyl-4'-cyanobiphenyl, 40 ml of diethylene glycol, 4 ml of water and 2 g of sodium hydroxide were introduced into 200 ml three neck flask and heated with stirring for 25 hours, followed by acidifying with hydrochloric acid, separating by filtration and recrystallizing with glacial acetic acid to give 4.1 g of 4-n-hexyl-biphenyl-4'-carboxylic acid (II), which was a colorless crystal having a molecular formula of C19H22O2 (composition: C 80.8%, H 7.9%, O 11.3% as calculated values and C 80.4%, H 8.1%, O 11.5% as observed values) and a melting point of 170° -171° C and formed a smectic liquid crystal at temperatures exceeding the melting point.

후처리

  1. temperatureheated
  2. customseparating by filtration
  3. customrecrystallizing with glacial acetic acid

출처 및 근거

ORD 기록
ord-baf99e0fdc284093a7109547019dea7d
출처 데이터셋
uspto-grants-1977_04
특허 번호
US04017416

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