Piperonal → Bis(3,4-methylenedioxy)chalcone

HRID 339647

반응식

HRID 339647 반응식
[CH:1]1[C:6]([CH:7]=[O:8])=[CH:5][C:4]2[O:9][CH2:10][O:11][C:3]=2[CH:2]=1.[CH3:12][C:13]([C:15]1[CH:20]=[CH:19][C:18]2[O:21][CH2:22][O:23][C:17]=2[CH:16]=1)=O.[OH-].[Na+]>C(O)C>[CH2:22]1[O:21][C:18]2[CH:19]=[CH:20][C:15]([CH:13]=[CH:12][C:7]([C:6]3[CH:1]=[CH:2][C:3]4[O:11][CH2:10][O:9][C:4]=4[CH:5]=3)=[O:8])=[CH:16][C:17]=2[O:23]1

참가 물질

5

반응물 3

HCID 8438PiperonalHCID 14798Sodium HydroxideHCID 76622Acetopiperone

생성물 1

HCID 294346Bis(3,4-methylenedioxy)chalcone

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of piperonal (460 mg) and 3,4-methylenedioxyacetophenone (500 mg) in ethanol (20 ml) was treated with 1M NaOH solution (4 ml), then the mixture was stirred overnight. The pale yellow crystalline solid was filtered off, washed with water then cold aqueous ethanol and dried to give pure bis(3,4-methylenedioxy)chalcone DC-0006B (476 mg, 53%).

후처리

  1. filtrationThe pale yellow crystalline solid was filtered off
  2. washwashed with water
  3. dry with materialcold aqueous ethanol and dried

출처 및 근거

ORD 기록
ord-65bba51aa38742f684bf9a2217b6badf
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08895554B2

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