Furan → Phosphonic acid, 2-furanyl-, diethyl ester

HRID 354019

반응식

HRID 354019 반응식
[O:1]1[CH:5]=[CH:4][CH:3]=[CH:2]1.[Li]CCCC.[P:11](Cl)([O:16][CH2:17][CH3:18])([O:13][CH2:14][CH3:15])=[O:12]>C(OCC)C>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[P:11]([O:16][CH2:17][CH3:18])(=[O:12])[O:13][CH2:14][CH3:15]

참가 물질

5

반응물 3

HCID 8029FuranHCID 13139Diethyl chlorophosphateHCID 178418339Butyllithium

생성물 1

HCID 12485182Phosphonic acid, 2-furanyl-, diethyl ester

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

A solution of furan (1 mmole) in diethyl ether was treated with TMEDA (N,N,N′N′-tetramethylethylenediamine) (1 mmole) and nBuLi (2 mmole) at −78° C. for 0.5 h. Diethyl chlorophosphate (1.2 mmole) was added to the reaction mixture and stirred for another hour. Extraction and distillation gave diethyl 2-furanphosphonate as a clear oil.

후처리

  1. extractionExtraction and distillation

출처 및 근거

ORD 기록
ord-2cef6820965a4d6e82d57e609f00f9cd
출처 데이터셋
uspto-grants-2004_06
특허 번호
US06756360B1

연결된 노트

불러오는 중…