Pyridine → Glycidyl benzoate

HRID 364254

반응식

HRID 364254 반응식
[CH2:1]1[O:3][CH:2]1[CH2:4][OH:5].N1C=CC=CC=1.[C:12](Cl)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>CCOCC>[C:12]([O:5][CH2:4][CH:2]1[O:3][CH2:1]1)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

참가 물질

5

반응물 3

HCID 1049PyridineHCID 7412Benzoyl chlorideHCID 11164Glycidol

생성물 1

HCID 25998Glycidyl benzoate수율 60%

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

A mixture containing 14.8 g (0.2 mole) of glycidol, 150 ml of anhydrous ether, 16 g (0.4 mole) of pyridine and 28 g (0.2 mole) of benzoyl chloride was stirred at room temperature for 2 hours. The mixture was filtered and the ether was evaporated to leave an oil. This oil was distilled to give 21 g (60%) of colorless oil: b.p. 92° C./0.5 mm Hg. The NMR and IR spectra were consistent with the assigned structure.

후처리

  1. filtrationThe mixture was filtered
  2. customthe ether was evaporated
  3. customto leave an oil
  4. distillationThis oil was distilled

출처 및 근거

ORD 기록
ord-c63f62e849684cd993425acaf0a156f2
출처 데이터셋
uspto-grants-1986_08
특허 번호
US04604481

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