Acetyl chloride → Ethanone, 1-(4-octylphenyl)-

HRID 395940

반응식

HRID 395940 반응식
[Cl-].[Al+3].[Cl-].[Cl-].[CH2:5]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[C:19](Cl)(=[O:21])[CH3:20]>ClC(Cl)C>[CH2:5]([C:13]1[CH:14]=[CH:15][C:16]([C:19](=[O:21])[CH3:20])=[CH:17][CH:18]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

참가 물질

5

반응물 3

HCID 6367Acetyl chlorideHCID 16607OctylbenzeneHCID 6451240Aluminum(III) Chloride

생성물 1

HCID 66344Ethanone, 1-(4-octylphenyl)-

시약·촉매·용매 1

HCID 63651,1-Dichloroethane용매

실험 절차

Aluminum chloride (22.6 g) is suspended in dichloroethane (500 ml) and octylbenzene (16) (21.5 g) is added at room temperature. To the mixture is added acetyl chloride (8.87 g) under ice-cooling. The mixture is stirred at room temperature overnight. The reaction mixture is poured into ice water and extracted with ether. The organic layer is washed with brine and dried over sodium sulfate. The solvent is evaporated to give 4′-octylacetophenone (18′) as a colorless oil.

후처리

  1. temperaturecooling
  2. extractionextracted with ether
  3. washThe organic layer is washed with brine
  4. dry with materialdried over sodium sulfate
  5. customThe solvent is evaporated

출처 및 근거

ORD 기록
ord-f0335febdb6e4fc9a41e2e6dafd45797
출처 데이터셋
uspto-grants-2003_08
특허 번호
US06605744B2

연결된 노트

불러오는 중…