Dichloromethane → 1-Chloro-4-acetyl-cyclohexene

HRID 414649

반응식

HRID 414649 반응식
[CH:1]([C:3]([CH3:5])=[O:4])=[CH2:2].[Cl-].[Al+3].[Cl-].[Cl-].C(Cl)Cl.[CH2:13]=[CH:14][C:15]([Cl:17])=[CH2:16]>O>[Cl:17][C:15]1[CH2:14][CH2:13][CH:1]([C:3](=[O:4])[CH3:5])[CH2:2][CH:16]=1

참가 물질

6

반응물 4

HCID 6344DichloromethaneHCID 6570Methyl vinyl ketoneHCID 31369ChloropreneHCID 6451240Aluminum(III) Chloride

생성물 1

HCID 143656601-Chloro-4-acetyl-cyclohexene

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
25 °C

실험 절차

To a solution of 98.1 parts of methyl vinyl ketone, 187 parts of anhydrous aluminum chloride and 1980 parts of methylene chloride was added 123 parts of chloroprene and the mixture was stirred at 25° C. for three hours and left standing for another 16 hours. Water was added to the reaction mixture and the organic layer was washed with 5% hydrochloric acid. Distillation gave a center cut of 61 parts of 1-chloro-4-acetyl-cyclohexene (125°-6° C./20 mm Hg). Reference: A. A. Petrov and N. P. Sopov, CA 42, 1910h (1948).

후처리

  1. waitleft
  2. waitstanding for another 16 hours
  3. washthe organic layer was washed with 5% hydrochloric acid
  4. distillationDistillation

출처 및 근거

ORD 기록
ord-19e3802694574392bda66521ea4de726
출처 데이터셋
uspto-grants-1988_12
특허 번호
US04792618

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