Hydrochloric Acid → 2,6-Di-tert-butyl-4-(chloromethyl)phenol

HRID 444107

반응식

HRID 444107 반응식
[OH:1][C:2]1[C:9]([C:10]([CH3:13])([CH3:12])[CH3:11])=[CH:8][C:5]([CH2:6]O)=[CH:4][C:3]=1[C:14]([CH3:17])([CH3:16])[CH3:15].[ClH:18]>CCCCCC>[OH:1][C:2]1[C:9]([C:10]([CH3:13])([CH3:12])[CH3:11])=[CH:8][C:5]([CH2:6][Cl:18])=[CH:4][C:3]=1[C:14]([CH3:17])([CH3:16])[CH3:15]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 6929Butylated hydroxymethylphenol

생성물 1

HCID 123786012,6-Di-tert-butyl-4-(chloromethyl)phenol

시약·촉매·용매 1

HCID 8058Hexane용매

실험 절차

176 grams of 4-hydroxy-3,5-di-tert-butyl-benzyl alcohol was slurried in 350 ml of hexane. 240 cc of concentrated HCl was added to the slurry and stirred overnight. The two phases were allowed to separate and the hexane phase washed twice with water. The dried hexane was then extracted with magnesium sulfate and filtered. Rotofilm evaporation yielded 168 grams of product--a pungent yellow liquid.

후처리

  1. customto separate
  2. washthe hexane phase washed twice with water
  3. extractionThe dried hexane was then extracted with magnesium sulfate
  4. filtrationfiltered
  5. customRotofilm evaporation

출처 및 근거

ORD 기록
ord-0c6429c18bae40c796f71c081f89e807
출처 데이터셋
uspto-grants-1981_04
특허 번호
US04263154

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