홈MCP워크벤치Skills
홈워크벤치알림마이페이지
llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
  1. 홈
  2. /반응

Hydrochloric Acid → 2-(Dimethoxymethyl)-4,6-dihydroxy-2,5,7,8-tetramethylchroman

HRID 462583
노트
인쇄 미리보기

반응식

HRID 462583 반응식
[CH3:1][O:2][CH:3]([O:20][CH3:21])[C:4]1([CH3:19])[CH2:13][C:12](=[O:14])[C:11]2[C:6](=[C:7]([CH3:18])[C:8]([CH3:17])=[C:9]([OH:16])[C:10]=2[CH3:15])[O:5]1.[BH4-].[Na+].[OH-].[Na+].Cl>CO>[CH3:21][O:20][CH:3]([O:2][CH3:1])[C:4]1([CH3:19])[CH2:13][CH:12]([OH:14])[C:11]2[C:6](=[C:7]([CH3:18])[C:8]([CH3:17])=[C:9]([OH:16])[C:10]=2[CH3:15])[O:5]1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 4311764Sodium borohydride2회HCID 130515362-(Dimethoxymethyl)-6-hydroxy-2,5,7,8-tetramethyl-chroman-4-one

생성물 1

HCID 130515402-(Dimethoxymethyl)-4,6-dihydroxy-2,5,7,8-tetramethylchroman수율 95%

시약·촉매·용매 1

HCID 887
Methanol
용매

실험 절차

9.4 g (32 mmoles) of the product from Example 2 were reacted with 2.43 g (64 mmoles) NaBH4 in 100 ml of methanol at 20°-60° C. After 6 hours, a further 2.43 g of NaBH4 were added, after which the reaction mixture was stirred at room temperature for 16 hours. 100 ml of 3N NaOH were then added, and the mixture was neutralized with dilute hydrochloric acid and then extracted with ether, a brown oil being obtained as the crude product in 95% yield. IR: 3,600 (broad) cm-1.

후처리

  1. extractionextracted with ether

출처 및 근거

ORD 기록
ord-3b31a94508974d0fa5a521efc2916cd5
출처 데이터셋
uspto-grants-1985_05
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US04515975

반응 노트

불러오는 중…

이 페이지에서참가 물질실험 절차후처리출처 및 근거반응 노트