Potassium Hydroxide → 1-Chloro-4-(3-phenylpropyl)benzene

HRID 463513

반응식

HRID 463513 반응식
[C:1]1([CH2:7][CH2:8][C:9]([C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][CH:12]=2)=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.O.NN.[OH-].[K+]>C(O)COCCO>[Cl:17][C:14]1[CH:13]=[CH:12][C:11]([CH2:9][CH2:8][CH2:7][C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[CH:16][CH:15]=1

참가 물질

5

반응물 3

HCID 14797Potassium HydroxideHCID 24654Hydrazine hydrate (1:1)HCID 2473444'-Chloro-3-phenylpropiophenone

생성물 1

HCID 133008571-Chloro-4-(3-phenylpropyl)benzene

시약·촉매·용매 1

HCID 8117Diethylene Glycol용매

실험 절차

p-chlorophenyl phenylethyl ketone (25 g) was refluxed with hydrazine hydrate (13 g) and potassium hydroxide (18 g) in Digol (diethylene glycol) for one hour. The mixture was then distilled until the solution temperature in the still reached 175°. The mixture was then refluxed for 3 hours, cooled, poured into water and extracted with petroleum ether (Bpt 40°-60°). Evaporation of the extracts gave 1-(4-chlorophenyl)-3-phenylpropane Bbt. 110°/10-3 mm.

후처리

  1. distillationThe mixture was then distilled until the solution temperature in the still reached 175°
  2. temperatureThe mixture was then refluxed for 3 hours
  3. temperaturecooled
  4. additionpoured into water
  5. extractionextracted with petroleum ether (Bpt 40°-60°)
  6. customEvaporation of the extracts

출처 및 근거

ORD 기록
ord-3ea19a854acc474080cbdd3124680918
출처 데이터셋
uspto-grants-1985_05
특허 번호
US04520007

연결된 노트

불러오는 중…