Piperidine → 2,6-Dimethyl-6-piperidino-4-hepten-2-ol
반응식
[CH3:1][C:2]([CH3:5])=[CH:3]Br.[CH3:6][C:7]([OH:11])([CH:9]=[CH2:10])[CH3:8].[NH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>C([O-])(=O)C.[Pd+2].C([O-])(=O)C>[CH3:6][C:7]([OH:11])([CH2:9][CH:10]=[CH:1][C:2]([CH3:5])([N:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)[CH3:3])[CH3:8]참가 물질
6
실험 절차
A mixture of 10 mmoles 2-methyl-1-bromo-1-propene, 12.5 mmoles 2-methyl-3-buten-2-ol, 30 mmoles piperidine, 0.20 mmole palladium acetate and 0.40 mmole triphenylphosphine was reacted at 100° C. There was produced 61% of a mixture of nonadienols, 31% 2,6-dimethyl-6-piperidino-4-hepten-2-ol and 6% of what is believed to be 2,6-dimethyl-4-piperidino-5-hepten-2-ol.
후처리
- customwas reacted at 100° C
출처 및 근거
- ORD 기록
- ord-2a8da2881cb74fe29c07cbad6f53654a
- 출처 데이터셋
- uspto-grants-1979_11
- 특허 번호
- US04175187
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