Carbazole → 9-Acetyl-9H-carbazole

HRID 49456

반응식

HRID 49456 반응식
[CH:1]1[C:13]2[NH:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.B(F)(F)F.[CH3:18][CH2:19][O:20]CC>C(OC(=O)C)(=O)C>[C:19]([N:12]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[C:13]1=[CH:1][CH:2]=[CH:3][CH:4]=2)(=[O:20])[CH3:18]

참가 물질

4

반응물 2

HCID 6854CarbazoleHCID 8000Boron trifluoride etherate

생성물 1

HCID 958379-Acetyl-9H-carbazole

시약·촉매·용매 1

HCID 7918Acetic Anhydride용매

반응 조건

온도
0 °C

실험 절차

Carbazole (100.24 g) was suspended in acetic anhydride (300 mL) with catalytic boron trifluoride etherate (0.65 mL) and the solution refluxed for 25 min. then cooled to 0° C. and the solid was then collected and recrystallized from hexane to give 82.65 g 9-acetyl-carbazole.

후처리

  1. temperaturethe solution refluxed for 25 min.
  2. customthe solid was then collected
  3. customrecrystallized from hexane

출처 및 근거

ORD 기록
ord-5daec04b8dd84e07a58c039f40a8ecf2
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06706753B2

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