3-Phenylprop-2-En-1-Ol → 3-Phenylprop-2-Enal

HRID 565126

반응식

HRID 565126 반응식
[C:1]1([CH:7]=[CH:8][CH2:9][OH:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.COC1C=C(C=CC=1OC)C=O.ON1C2C=CC=CC=2N=N1.CCN1C2C=CC(S([O-])(=O)=O)=CC=2S/C/1=N\N=C1/SC2C=C(S([O-])(=O)=O)C=CC=2N/1CC.[NH4+].[NH4+]>C(O)C>[C:1]1([CH:7]=[CH:8][CH:9]=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

6

반응물 4

HCID 3083-Phenylprop-2-En-1-OlHCID 8419VeratraldehydeHCID 757711-HydroxybenzotriazoleHCID 95704746-benzothiazolesulfonic acid, 2,2'-azinobis(3-ethyl-2,3-dihydro-, diammonium salt

생성물 1

HCID 3073-Phenylprop-2-Enal수율 48%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

213 mg (1.59 mmol) of 3-phenyl-2-propen-1-ol in 1.1 ml of ethanol were treated at 45° C. with stirring into 22 ml of buffer solution (see Example 1) with 24.3 mg (0.180 mmol) of 1-hydroxy-1H-benzotriazole. After approx. 10 minutes, 5 ml of an aqueous solution of 2 mg/ml laccase from Trametes versicolor (specific activity approx. 18 IU/mg, defined with ABTS as the substrate) were added. After 3 hours in contact with the air, 48% of 3-phenyl-2-propenal were formed (GC analysis), and a further 24.3 mg of HOBT and 5 ml of laccase solution were added. GC analysis after 6 hours revealed complete conversion into 3-phenyl-2-propenal.

후처리

  1. additionwere added
  2. waitAfter 3 hours in contact with the air

출처 및 근거

ORD 기록
ord-d1bcdfe08e014a60849b73cee79e34d3
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06169213A

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