Hydrochloric Acid → HCID 21266158, 화합물

HRID 566424

반응식

HRID 566424 반응식
[CH2:1]([NH2:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].[C@@H:16]12[C:25](=O)[O:24][C:22](=[O:23])[C@@H:17]1[CH2:18][CH:19]=[CH:20][CH2:21]2.[BH4-].[Na+].Cl>O.CC(O)C>[OH:24][CH2:25][CH:16]1[CH:17]([C:22]([NH:15][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])=[O:23])[CH2:18][CH:19]=[CH:20][CH2:21]1

참가 물질

7

반응물 4

HCID 313Hydrochloric AcidHCID 16217TetradecylamineHCID 98495Tetrahydrophthalic anhydride, cis-HCID 4311764Sodium borohydride

생성물 1

HCID 21266158HCID 21266158, 화합물수율 93.1%

시약·촉매·용매 2

HCID 962Water용매HCID 3776Isopropanol용매

반응 조건

온도
140 °C

실험 절차

1-Tetradecylamine (3.51 g) was added to cis-4-cyclohexene-1,2-dicarboxylic anhydride (2.50 g) and stirred for 5 hours at 140° C. The reaction mixture was suspended into a mixed solution of 2-propanol (125 ml) and water (21 ml) and then sodium borohydride (3.11 g) was added thereto at room temperature. After being stirred for 67.5 hours at room temperature, the reaction mixture was acidified with dilute hydrochloric acid. The resulting solid was collected by filtration under a vacuum, washed with water, and dried, thereby yielding the entitled compound (5.38 g) as white solid.

후처리

  1. customat room temperature
  2. stirringAfter being stirred for 67.5 hours at room temperature
  3. filtrationThe resulting solid was collected by filtration under a vacuum
  4. washwashed with water
  5. customdried

출처 및 근거

ORD 기록
ord-478abe3bf9a9404bbfcca86e0ea2e081
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06174885B1

연결된 노트

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