Methyl Methacrylate → Retinol Palmitate

HRID 585417

반응식

HRID 585417 반응식
[CH3:1][C:2]1[CH2:7][CH2:6][CH2:5][C:4]([CH3:9])([CH3:8])[C:3]=1/[CH:10]=[CH:11]/[C:12](/[CH3:21])=[CH:13]/[CH:14]=[CH:15]/[C:16](/[CH3:20])=[CH:17]/[CH2:18][OH:19].[CH3:22][C:23]([C:25]([O:27]C)=O)=C>O.C(OCC)(=O)C>[CH3:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:3][CH2:2][CH2:7][CH2:6][CH2:22][CH2:23][C:25]([O:19][CH2:18]/[CH:17]=[C:16](/[CH:15]=[CH:14]/[CH:13]=[C:12](/[CH:11]=[CH:10]/[C:3]1[C:4]([CH3:8])([CH3:9])[CH2:5][CH2:6][CH2:7][C:2]=1[CH3:1])\[CH3:21])\[CH3:20])=[O:27]

참가 물질

5

반응물 2

HCID 6658Methyl MethacrylateHCID 445354Retinol

생성물 1

HCID 5280531Retinol Palmitate

시약·촉매·용매 2

HCID 962Water용매2회HCID 8857Ethyl Acetate용매2회

실험 절차

An aqueous phase was prepared by dissolving 0.5 g of poly(vinyl alcohol) in 50 ml water saturated by 6 ml of ethyl acetate. An organic phase was prepared by dissolving 0.075 g retinol palmitate, 0.1 g mineral oil, 0.01 g of an antioxidant (chosen from BHA, BHT, tocopherol or their mixture) and 0.815 g PMMA in 5 ml of ethyl acetate. The organic phase was poured into the aqueous phase while stirring and then 100 ml of fresh water were added. The microcapsules formed were filtered, washed by water and dried at the temperature no higher 20° C. An average diameter of the microcapsules was 40 μm.

후처리

  1. customAn aqueous phase was prepared
  2. customAn organic phase was prepared
  3. additionThe organic phase was poured into the aqueous phase
  4. customThe microcapsules formed
  5. filtrationwere filtered
  6. washwashed by water
  7. customdried at the temperature no higher 20° C

출처 및 근거

ORD 기록
ord-d9a7a0fabf954438ac33d04084d9702b
출처 데이터셋
uspto-grants-2005_08
특허 번호
US06932984B1

연결된 노트

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