Hydrochloric Acid → HCID 178503824, 화합물

HRID 597404

반응식

HRID 597404 반응식
Cl.NC1NC=C(CO)N=1.C1(C([O-])=C([N+]([O-])=O)C=C([N+]([O-])=O)C=1)[N+]([O-])=O.Cl.Cl.NCCS.[NH2:32][C:33]1[NH:34][CH:35]=[C:36]([CH2:38][S:39][CH2:40][CH2:41][NH2:42])[N:37]=1.[N+:43]([CH:46]=[C:47](SC)[S:48][CH3:49])([O-:45])=[O:44]>>[N+:43]([CH:46]=[C:47]([S:48][CH3:49])[NH:42][CH2:41][CH2:40][S:39][CH2:38][C:36]1[N:37]=[C:33]([NH2:32])[NH:34][CH:35]=1)([O-:45])=[O:44]

참가 물질

7

반응물 6

HCID 313Hydrochloric AcidHCID 9082Cysteamine HydrochlorideHCID 836231,1-Bis(methylthio)-2-nitroethyleneHCID 4432340PicrateHCID 178479151HCID 178479151, 화합물HCID 178511470HCID 178511470, 화합물

생성물 1

HCID 178503824HCID 178503824, 화합물

실험 절차

Reaction of 2-amino-4-hydroxymethylimidazole hydrochloride (which is obtained by treating the picrate salt with hydrochloric acid) with cysteamine hydrochloride and reaction of the resulting 2-amino-4-[(2-aminoethyl)-thiomethyl]imidazole with 1-nitro-2,2-bis-methylthioethylene according to the procedure of Example 8(i) gives 1-nitro-2-methylthio-2-[2-((2-amino-4-imidazolyl)methylthio)-ethylamino]ethylene. Finally, reaction with 2-[(2-aminoethyl)thiomethyl]-3-chloropyridine by the procedure of Example 1 (a)(ii) produces the title compound.

후처리

  1. customis obtained

출처 및 근거

ORD 기록
ord-b1c6cfb86095455ab6118d489d5799bb
출처 데이터셋
uspto-grants-1977_03
특허 번호
US04013769

연결된 노트

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