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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline → Biphenyl

HRID 608913
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HRID 608913 반응식
CN(C)C(=NC(C)(C)C)N(C)C.CN(C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.O=C(NCc1ccc(F)cc1)c1nc(Br)c2cccnc2c1O>CCC(C)(C)O.CN(C)c1ccc([PH](C(C)(C)C)(C(C)(C)C)[Pd]2([O]S(C)(=O)=O)[NH]c3ccccc3-c3cccc[c]32)cc1.CS(C)=O.O>CN(C)c1ccc(-c2nc(C(=O)NCc3ccc(F)cc3)c(O)c3ncccc23)cc1
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참가 물질

10

반응물 2

HCID 2758659N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)anilineHCID 223464015-bromo-N-(4-fluorobenzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamide

생성물 3

HCID 7095BiphenylHCID 223464015-bromo-N-(4-fluorobenzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamideHCID 178482693HCID 178482693, 화합물

시약·촉매·용매 5

HCID 178482905HCID 178482905, 화합물촉매HCID 679Dimethyl Sulfoxide용매3회HCID 962Water용매HCID 64052-Methyl-2-butanol용매HCID 35715812-tert-Butyl-1,1,3,3-tetramethylguanidine기타

후처리

  1. additionAfter 22 hours the crude reactions were diluted with 3 x 1 uL 0.5 M AcOH in DMSO (containing PhPh as an internal standard). The reactions were mixed after each dispense operation.
  2. aliquotMosquito(R) was used to transfer 1 uL of each quenched reaction from the 1,536-well reaction plate to 384-well analytical plates containing 60 uL DMSO for analysis.

출처 및 근거

ORD 기록
ord-c0981492aadc48d3ac8240bcb2f78818
출처 데이터셋
Cernak miniaturized Suzuki Cross-Coupling 12x10 Informer Library
DOI
10.1038/s44160-023-00351-1
원본 링크
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