Benzoyl chloride → Methyl Benzoate

HRID 65128

반응식

HRID 65128 반응식
C(Cl)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:10](=O)([O:13][CH3:14])[O:11]C>[Br-].C([P+](CCCC)(CCCC)CCCC)CCC.S1(CCCC1)(=O)=O>[C:10]([O:13][CH3:14])(=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

5

반응물 2

HCID 7412Benzoyl chlorideHCID 12021Dimethyl Carbonate

생성물 1

HCID 7150Methyl Benzoate수율 93%

시약·촉매·용매 2

HCID 76564Tetrabutylphosphonium bromide촉매HCID 31347Sulfolane용매

반응 조건

온도
150 °C

실험 절차

A mixture of 7.03 g (0.05 g mole) of benzoyl chloride, 4.5 g (0.05 g mole) of dimethyl carbonate, and 0.85 g (0.0025 g mole) of tetra-n-butyl phosphonium bromide (TBPB) in 25 ml of sulfolane was heated at 150° C. in a reaction flask equipped with reflux condenser. After 22 hours, the condenser was replaced by a distillation head and 6.3 g (93 percent yield) of methyl benzoate distilled at 83° C.-85° C./17 mm.

후처리

  1. customequipped
  2. temperaturewith reflux condenser

출처 및 근거

ORD 기록
ord-cd7c469e8ad042e59278ed20576ac749
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04612386

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