Nitromethane → Methyl 4-(2-nitroethenyl)benzoate

HRID 6731

반응식

HRID 6731 반응식
[OH-].[Na+].[CH3:3][O:4][C:5](=[O:14])[C:6]1[CH:11]=[CH:10][C:9]([CH:12]=O)=[CH:8][CH:7]=1.[N+:15]([CH3:18])([O-:17])=[O:16]>CO>[CH3:3][O:4][C:5](=[O:14])[C:6]1[CH:11]=[CH:10][C:9]([CH:12]=[CH:18][N+:15]([O-:17])=[O:16])=[CH:8][CH:7]=1

참가 물질

5

반응물 3

HCID 6375NitromethaneHCID 14798Sodium HydroxideHCID 15294Methyl 4-Formylbenzoate

생성물 1

HCID 896295Methyl 4-(2-nitroethenyl)benzoate

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Sodium hydroxide (1 N, 2.3 mL) was added dropwise to 4-formyl-benzoic acid methyl ester (0.33 g) and nitromethane (0.11 ml) in 5 mL methanol at 0° C. The solution was acidified after 0.5 h and a precipitate was formed. The precipitate was isolated by filtration to give 228 mg of 4-(2-nitro-vinyl)-benzoic acid methyl ester.

후처리

  1. customa precipitate was formed
  2. customThe precipitate was isolated by filtration

출처 및 근거

ORD 기록
ord-bbf5b318502845ec93a68e348bf67846
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07084154B2

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