Hydrochloric Acid → 2-Amino-5-bromo-3-iodobenzenesulphonic acid

HRID 727435

반응식

HRID 727435 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][C:3]=1[S:9]([OH:12])(=[O:11])=[O:10].[I:13]Cl.Cl>CO>[NH2:1][C:2]1[C:7]([I:13])=[CH:6][C:5]([Br:8])=[CH:4][C:3]=1[S:9]([OH:12])(=[O:11])=[O:10]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 24640Iodine chlorideHCID 150236152-Amino-5-bromobenzenesulphonic acid

생성물 1

HCID 189193852-Amino-5-bromo-3-iodobenzenesulphonic acid

시약·촉매·용매 1

HCID 887Methanol용매

반응 조건

온도
90 °C

실험 절차

To 45 g (176 mmol) of 2-amino-5-bromobenzenesulphonic acid are added 46 g (282 mmol) of iodine chloride, 400 ml of aqueous 1N hydrochloric acid solution and 400 ml of methanol. The mixture is heated at 90° C. for 18 hours and concentrated under reduced pressure, and the residue is crystallized from ethanol.

후처리

  1. concentrationconcentrated under reduced pressure
  2. customthe residue is crystallized from ethanol

출처 및 근거

ORD 기록
ord-c7555d9d61194faeb8c71463882c07bf
출처 데이터셋
uspto-grants-1998_01
특허 번호
US05712393

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